The Human Proteome Project, by characterizing all 20,300 genes of the known genome, will generate the map of the protein based molecular architecture of the human body and become a resource to help elucidate biological and molecular function and advance diagnosis and treatment of diseases.

• Chromosome-based Human Proteome Project (C-HPP)
• Biology/Disease Human Proteome Project (B/D-HPP)

Overview:

The Human Proteome Project is an international project organized by the Human Proteome Organization (HUPO) that aims to revolutionize our understanding of the human proteome via a coordinated effort by many research laboratories around the world...
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Latest News:

• 2015-12-04: 12 more C-HPP articles are available in the December issue of the Journal of Proteome Research.
• 2015-09-08: The HUPO 2015 Chromosome-centric HPP special issue in the Journal of Proteome Research is released, including 30 new publications from the HPP.
• 2015-04-21: C-HPP Newsletter No. 4 - April 2015 is now available.
• 2014-07-07: Program for the C-HPP August 9th Workshop in Bangkok is now available.
• 2014-03-13: C-HPP Newsletter No. 3 - March 2014 is now available.
• 2013-07-01: The deadline for submission to the JPR HPP 2014 special issue is August 1. As a reminder to all authors: all raw data and metadata must be submitted according to the guidelines in time for manuscript submission.
• 2013-06-21: The second phase of the 2013 Chromosome-centric HUPO HPP special issue in the Journal of Proteome Research is released, including 15 new publications from the HPP for a total of 48 articles in 2013 JPR special issue.
• 2013-06-11: C-HPP June 2013 Newsletter is now available.
• 2013-05-21: Spring edition of the HUPO newsletter HUPOST includes a story on the C-HPP workshop in Berlin
• 2013-01-28: Winter edition of the HUPO newsletter HUPOST includes an extensive story on the current status of the HPP
• 2013-01-01: The Chromosome-centric HUPO HPP special issue in the Journal of Proteome Research is released, including 33 new publications from the HPP.

Documents:

• 12 new HPP publications in the December 2015 issue of the Journal of Proteome Research
• 30 new HPP publications in the C-HPP September 2015 special issue of the Journal of Proteome Research
• Aebersold et al.(2014): Highlights of B/D-HPP and HPP Resource Pillar Workshops at 12th Annual HUPO World Congress in Proteomics (PDF)
• 6 additional HPP publications as an addition to the set of 2014 HPP publications in the Journal of Proteome Research
• 32 new HPP publications in a C-HPP part II January 2014 special issue of the Journal of Proteome Research
• 15 HPP publications completing the 2013 C-HPP special issue of the Journal of Proteome Research
• 33 HPP publications in a C-HPP January 2013 special issue of the Journal of Proteome Research
• "Uniting ENCODE with genome-wide proteomics" - Paik and Hancock (2012) Nature Biotechnology, 30, 1065-7
• "Reproducible Quantification of Cancer-associated Proteins in Body Fluids using Targeted Proteomics" - Hüttenhain et al. (2012) Sci Transl Med., 4(142), 142ra94
• "New and Improved Proteomics Technologies for Understanding Complex Biological Systems: Addressing a Grand Challenge in the Life Sciences" - Hood et al. (2012) Proteomics, Jul 16. doi: 10.1002/pmic.201270086. [Epub ahead of print]
• "The Human Proteome - a Scientific Opportunity for Transforming Diagnostics, Therapeutics, and Healthcare" - Vidal et al. (2012) Clin Proteomics, 9(1), 6
• "Standard guidelines for the chromosome-centric human proteome project" - Paik et al. (2012) J Proteome Res., 11, 2005-13
• "The human proteome project: Current state and future direction" - Legrain et al., (2011) Mol Cell Proteomics, mcp.O111.009993
• "Antibody-based protein profiling of the human chromosome 21" - Uhlén et al. (2011) Mol Cell Proteomics mcp.M111.013458
• "A Chromosome-Centric Human Proteome Project to Characterize the Sets of Proteins Encoded in the Genome" - Paik et al. (2012) Nature Biotechnology, 30, 221-223

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